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The Peter Attia Drive

Longevity 101: a foundational guide to Peter’s frameworks for longevity, and understanding CVD, cancer, neurodegenerative disease, nutrition, exercise, sleep, and more (re-broadcast)

Monday, October 27, 2025

#370 - AMA #76: Peter evaluates longevity drugs, aspirin for CVD, and strategies to improve muscle mass — proven, promising, fuzzy, noise, or nonsense?

Monday, October 27, 2025

#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

Monday, October 20, 2025

#368 ‒ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

Monday, October 13, 2025

#367 - Tylenol, pregnancy, and autism: What recent studies show and how to interpret the data

Monday, October 6, 2025

#366 ‒ Transforming education with AI and an individualized, mastery-based education model | Joe Liemandt

Monday, September 29, 2025

#365 ‒ Training for longevity: A roundtable on building strength, preventing injury, meeting protein needs, guidance for women and youth athletes, and more | Gabrielle Lyon, Mike Boyle, Jeff Cavaliere

Monday, September 22, 2025

#364 – AMA #75: Diets: how to evaluate and implement any diet including keto, carnivore, vegan, Mediterranean, and more

Monday, September 15, 2025

#363 ‒ A new frontier in neurosurgery: restoring brain function with brain-computer interfaces, advancing glioblastoma care, and new hope for devastating brain diseases | Edward Chang, M.D.

Monday, September 8, 2025

Lower back pain: causes, treatment, and prevention of lower back injuries and pain | Stuart McGill, Ph.D. (#287 rebroadcast)

Monday, September 1, 2025

#362 ‒ Understanding anxiety: defining, assessing, and treating health anxiety, OCD, and the spectrum of anxiety disorders | Josh Spitalnick, Ph.D., A.B.P.P.

Monday, August 25, 2025

#361 - AMA #74: Sugar and sugar substitutes: weight control, metabolic effects, and health trade-offs

Monday, August 18, 2025

#360 ‒ How to change your habits: why they form and how to build or break them | Charles Duhigg, M.B.A

Monday, August 11, 2025

#359 ‒ How metabolic and immune system dysfunction drive the aging process, the role of NAD, promising interventions, aging clocks, and more | Eric Verdin, M.D.

Monday, August 4, 2025

#358 ‒ Peter’s takeaways on navigating HRT, rejuvenating the face, understanding the biology of aging, optimizing fertility, and learning to live well from the dying | Quarterly Podcast Summary #6

Monday, July 28, 2025

#357 ‒ A new era of longevity science: models of aging, human trials of rapamycin, biological clocks, promising compounds, and lifestyle interventions | Brian Kennedy, Ph.D.

Monday, July 21, 2025

#356 - AMA #73: Preserving brain health, optimizing exercise programming, improving body composition, and more

Monday, July 14, 2025

Navigating bone health: early life influences and advanced strategies for improvement and injury prevention (#214 rebroadcast)

Monday, July 7, 2025

#355 – Skincare strategies, the science of facial aging, and cosmetic-intervention guidance | Tanuj Nakra, M.D. & Suzan Obagi, M.D.

Monday, June 30, 2025

#354 – What the dying can teach us about living well: lessons on life and reflections on mortality | BJ Miller, M.D. and Bridget Sumser, L.C.S.W.

Monday, June 23, 2025

#353 - AMA #72: Fasting: benefits for body composition and disease prevention, potential risks, and Peter’s updated practical framework

Monday, June 16, 2025

#352 ‒ Female fertility: optimizing reproductive health, diagnosing and treating infertility and PCOS, and understanding the IVF process | Paula Amato, M.D.

Monday, June 9, 2025

#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Monday, June 2, 2025

#350 ‒ Injury prevention, recovery, and performance optimization for every decade | Kyler Brown, D.C.

Monday, May 26, 2025

#349 - AMA #71: Building strength and muscle mass: how to optimize training, nutrition, and more for longevity

Monday, May 19, 2025

#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

Monday, May 12, 2025

#347 – Peter’s takeaways on mastering sleep, dealing with chronic pain, developing breakthrough cancer drugs, transforming healthcare with AI, advancing radiation therapy, and healing trauma | Quarterly Podcast Summary #5

Monday, May 5, 2025

#346 - Scaling biotech and improving global health: lessons from an extraordinary career in medicine | Susan Desmond-Hellmann, M.D., M.P.H.

Monday, April 28, 2025

#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

Monday, April 21, 2025

#344 - AMA #70: Nicotine: impact on cognitive function, performance, and mood, health risks, delivery modalities, and smoking cessation strategies

Monday, April 14, 2025

#343 – The evolving role of radiation: advancements in cancer treatment, emerging low-dose treatments for arthritis, tendonitis, and injuries, and addressing misconceptions | Sanjay Mehta, M.D.

Monday, April 7, 2025

#342 ‒ Aging well: Peter shares strategies for improving longevity with residents at a senior living center

Monday, March 31, 2025

#341 - Overcoming insomnia: improving sleep hygiene and treating disordered sleep with cognitive behavioral therapy for insomnia | Ashley Mason, Ph.D.

Monday, March 24, 2025

#340 - AMA #69: Scrutinizing supplements: creatine, fish oil, vitamin D, and more—a framework for understanding effectiveness, quality, and individual need

Monday, March 17, 2025

#339 - Unpacking trauma: How early wounds shape behavior and the path toward healing | Jeff English

Monday, March 10, 2025

#338 ‒ Peter’s takeaways on aerobic exercise and VO2 max, insulin resistance, rising healthcare costs, treating children with autism and ADHD, and strength training | Quarterly Podcast Summary #4

Monday, March 3, 2025

#337 - Insulin resistance masterclass: The full body impact of metabolic dysfunction and prevention, diagnosis, and treatment | Ralph DeFronzo, M.D.

Monday, February 24, 2025

#336 - AMA #68: Fasting, well-balanced diets, alcohol, exercise for busy people, wearables, emotional health, assessing cardiovascular health, and more

Monday, February 17, 2025

#335 ‒ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

Monday, February 10, 2025

#334 - Cardiovascular disease, the number one killer: development, biomarkers, apoB, cholesterol, brain health, and more | Tom Dayspring, M.D.

Monday, February 3, 2025

#333 ‒ Longevity roundtable — the science of aging, geroprotective molecules, lifestyle interventions, challenges in research, and more | Steven Austad, Matt Kaeberlein, Richard Miller

Monday, January 27, 2025

#332 - AMA #67: Microplastics, PFAS, and phthalates: understanding health risks and a framework for minimizing exposure and mitigating risk

Monday, January 20, 2025

#331 ‒ Optimizing endurance performance: metrics, nutrition, lactate, and more insights from elite performers | Olav Aleksander Bu (Pt. 2)

Monday, January 13, 2025

#330 – Autism, ADHD, and Anxiety: Understanding the rise in autism and a multidisciplinary approach to diagnosis and treatment of each condition in children | Trenna Sutcliffe, M.D.

Monday, January 6, 2025

Building & Changing Habits | James Clear (#183 rebroadcast)

Monday, December 30, 2024

#329 ‒ Special AMA: Peter on exercise, important labs, building good habits, promising longevity research, and more

Monday, December 16, 2024

#328 - AMA #66: Optimizing nutrition for health and longevity: myth of a “best” diet, complexities of nutrition science, and practical steps for building a sustainable diet

Monday, December 9, 2024

#327 - Choices, costs, and challenges in US healthcare: insurance intricacies, drug pricing, economic impacts, and potential reforms | Saum Sutaria, M.D.

Monday, December 2, 2024

Optimizing life for maximum fulfillment | Bill Perkins (#237 rebroadcast)

Monday, November 25, 2024

#326 - AMA #65: Red light therapy: promising applications, mixed evidence, and impact on health and aging

Monday, November 18, 2024

#325 ‒ Peter’s key takeaways on bone health, calorie restriction and energy balance, dopamine and addiction, gene editing, and testosterone therapy safety with a prostate cancer diagnosis | Quarterly Podcast Summary #3

Monday, November 11, 2024

#324 ‒ Metabolism, energy balance, and aging: How diet, calorie restriction, and macronutrients influence longevity and metabolic health | Eric Ravussin, Ph.D.

Monday, November 4, 2024

#323 - CRISPR and the future of gene editing: scientific advances, genetic therapies, disease treatment potential, and ethical considerations | Feng Zhang, Ph.D.

Monday, October 28, 2024

#322 - Bone health for life: building strong bones, preventing age-related loss, and reversing osteoporosis with evidence-based exercise | Belinda Beck, Ph.D.

Monday, October 21, 2024

#321 – Dopamine and addiction: navigating pleasure, pain, and the path to recovery | Anna Lembke, M.D.

Monday, October 14, 2024

#320 – AMA 64: New insights on GLP-1 agonists (Ozempic, Wegovy, Mounjaro) - efficacy, benefits, risks, and considerations in the rapidly evolving weight-loss drug landscape

Monday, October 7, 2024

#319 ‒ Peter's key takeaways on liver health, heart rate variability, AI in medicine, klotho, and lactate metabolism | Quarterly Podcast Summary #2

Monday, September 30, 2024

#318 ‒ Cycling phenom and Tour de France champion Tadej Pogačar reveals his training strategies, on-bike nutrition, and future aspirations

Monday, September 23, 2024

#317 ‒ Reforming medicine: uncovering blind spots, challenging the norm, and embracing innovation | Marty Makary, M.D., M.P.H.

Monday, September 16, 2024

#316 - AMA #63: A guide for hair loss: causes, treatments, transplants, and sex-specific considerations

Monday, September 9, 2024

Improve your decision-making, frameworks for learning, backcasting, and more | Annie Duke (#60 rebroadcast)

Monday, September 2, 2024

#315 ‒ Life after near-death: a new perspective on living, dying, and the afterlife | Sebastian Junger

Monday, August 26, 2024

#314 ‒ Rethinking nutrition science: the evolving landscape of obesity treatment, GLP-1 agonists, protein, and the need for higher research standards | David Allison, Ph.D.

Monday, August 19, 2024

#313 - AMA #62: Protein’s impact on appetite and weight management, and uric acid's link to disease and how to manage levels

Monday, August 12, 2024

#312 - A masterclass in lactate: Its critical role as metabolic fuel, implications for diseases, and therapeutic potential from cancer to brain health and beyond | George A. Brooks, Ph.D.

Monday, August 5, 2024

#311 ‒ Longevity 101: a foundational guide to Peter's frameworks for longevity, and understanding CVD, cancer, neurodegenerative disease, nutrition, exercise, sleep, and more

Monday, July 29, 2024

#310 - The relationship between testosterone and prostate cancer, testosterone replacement therapy, and tools for predicting cancer aggressiveness and guiding therapy | Ted Schaeffer, M.D., Ph.D.

Monday, July 22, 2024

#309 ‒ AI in medicine: its potential to revolutionize disease prediction, diagnosis, and outcomes, causes for concern in medicine and beyond, and more | Isaac Kohane, M.D., Ph.D.

Monday, July 15, 2024

Zone 2 training: impact on longevity and mitochondrial function, how to dose frequency and duration, and more | Iñigo San-Millán, Ph.D. (#201 rebroadcast)

Monday, July 8, 2024

#308 - AMA #61: Sun exposure, sunscreen, and skin health: relationship between sun exposure and skin cancer, vitamin D production, and photoaging, how to choose a sunscreen, and more

Monday, July 1, 2024

#307 ‒ Exercise for aging people: where to begin, and how to minimize risk while maximizing potential | Peter Attia, M.D.

Monday, June 24, 2024

#306 - AMA #60: preventing cognitive decline, nutrition myths, lowering blood glucose, apoB, and blood pressure, and more

Monday, June 17, 2024

#305 ‒ Heart rate variability: how to measure, interpret, and utilize HRV for training and health optimization | Joel Jamieson

Monday, June 10, 2024

#304 – NEW: Introducing quarterly podcast summaries - Peter shares his biggest takeaways on muscle protein synthesis, VO2 max, toe strength, gut health, and more

Monday, June 3, 2024

#303 - A breakthrough in Alzheimer’s disease: the promising potential of klotho for brain health, cognitive decline, and as a therapeutic tool for Alzheimer's disease | Dena Dubal, M.D., Ph.D.

Monday, May 27, 2024

#302 - Confronting a metabolic epidemic: understanding liver health and how to prevent, diagnose, and manage liver disease | Julia Wattacheril, M.D., M.P.H.

Monday, May 20, 2024

#301 - AMA #59: Inflammation: its impact on aging and disease risk, and how to identify, prevent, and reduce it

Monday, May 13, 2024

#300 - Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, and more — promising interventions or just noise?

Monday, May 6, 2024

Special episode with Dax Shepard: F1 and the 30th anniversary of Ayrton Senna’s death

Monday, April 29, 2024

#299 ‒ Optimizing muscle protein synthesis: the crucial impact of protein quality and quantity, and the key role of resistance training | Luc van Loon, Ph.D.

Monday, April 22, 2024

#298 ‒ The impact of emotional health on longevity, self-audit strategies, improving well-being, and more | Paul Conti, M.D.

Monday, April 15, 2024

#297 - AMA #58: Iron: its role in health, testing methods, and strategies for preventing and managing iron deficiency

Monday, April 8, 2024

#296 ‒ Foot health: preventing and treating common injuries, enhancing strength and mobility, picking footwear, and more | Courtney Conley, D.C.

Monday, April 1, 2024

#295 ‒ Roadway death and injury: why everyone should care and what you can do to reduce risk | Mark Rosekind, Ph.D.

Monday, March 25, 2024

#294 ‒ Peak athletic performance: How to measure it and how to train for it from the coach of the most elite athletes on earth | Olav Aleksander Bu

Monday, March 18, 2024

#293 - AMA #57: High-intensity interval training: benefits, risks, protocols, and impact on longevity

Monday, March 11, 2024

#292 ‒ Rucking: benefits, gear, FAQs, and the journey from Special Forces to founding GORUCK | Jason McCarthy

Monday, March 4, 2024

#291 ‒ The role of testosterone in males and females, performance-enhancing drugs, sustainable fat loss, supplements, and more | Derek, More Plates More Dates Pt.2

Monday, February 26, 2024

#290 ‒ Liquid biopsies for early cancer detection, the role of epigenetics in aging, and the future of aging research | Alex Aravanis, M.D., Ph.D.

Monday, February 19, 2024

#289 - AMA #56: Cancer screening: pros and cons, screening options, interpreting results, and more

Monday, February 12, 2024

#288 ‒ The impact of gratitude, serving others, embracing mortality, and living intentionally | Walter Green

Monday, February 5, 2024

#287 ‒ Lower back pain: causes, treatment, and prevention of lower back injuries and pain | Stuart McGill, Ph.D.

Monday, January 29, 2024

#286 ‒ Journal club with Andrew Huberman: the impact of light exposure on mental health and an immunotherapy breakthrough for cancer treatment

Monday, January 22, 2024

#285 - AMA #55: Exercise: longevity-focused training, goal setting, improving deficiencies, managing emotional stress, and more

Monday, January 15, 2024

#284 ‒ Overcoming addictive behaviors, elevating wellbeing, thriving in an era of excess, and the scarcity loop | Michael Easter, M.A.

Monday, January 8, 2024

James Clear: Building & Changing Habits (#183 rebroadcast)

Monday, January 1, 2024

#283 ‒ Gut health & the microbiome: improving and maintaining the microbiome, probiotics, prebiotics, innovative treatments, and more | Colleen Cutcliffe, Ph.D.

Monday, December 18, 2023

#282 - AMA #54: Magnesium: risks of deficiency, how to correct it, supplement options, potential cognitive and sleep benefits, and more

Monday, December 11, 2023

#281 ‒ Longevity drugs, aging biomarkers, and updated findings from the Interventions Testing Program (ITP) | Rich Miller, M.D., Ph.D.

Monday, December 4, 2023

#280 ‒ Cultivating happiness, emotional self-management, and more | Arthur Brooks Ph.D.

Monday, November 27, 2023